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Maria Zambon

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Maria Caterina Zambon[1] FMedSci FRCPath, is a British virologist, director of reference microbiology for Public Health England and a professor. Her main research areas include influenza vaccination and influenza hemagglutination inhibition.[2]

Life and work

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In 1984, Zambon earned a PhD from the University of London (Imperial College) with a thesis titled "Inhibition of influenza virus replication by 1-aminoadamantane".[1] This work on "the mechanism of action of amantadine ... led directly to the identification of a novel class of viral proteins, viral ion channels (M2 protein)",[3] research in which she participated further in the following years.[4]

She leads her own research group devoted to respiratory virus diagnosis, surveillance and integrated clinical research programmes, with particular emphasis on influenza and other respiratory viruses.  She also coordinates several multinational European Union projects devoted to influenza vaccines and antivirals.  Primarily, her research concentrates on the diagnoses of viral infections in humans, with particular attention on "RNA viruses, the pathogenicity of influenza and development of new vaccines for respiratory viruses, particularly influenza".  In addition, she has been instrumental in the development of vaccines for avian influenza and took part of a successful UK consortium that conducted clinical trials of the H5, H7 and H9 vaccines.[3]

Zambon is one of the 23 attendees of the Scientific Advisory Group for Emergencies (Sage).[5] She was a member of the Coronaviridae Study Group of the International Committee on Taxonomy of Viruses and contributed to the scientific description of MERS-CoV's taxonomy.[6]

Maria Zambon and her colleague Joanna Ellis contributed to the development of the first real-time RT-PCR test for SARS-CoV-2, which was led by Christian Drosten.[7][8]

Honors

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In 2011, she was elected a fellow of the Academy of Medical Sciences.[9] She is a fellow of the Royal College of Pathologists.[10]

References

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  1. ^ a b Her thesis on 1 -aminoadamantane (also named amantadine) can be downloaded by using a link associated to the thesis' title in her Google Scholar profile.
  2. ^ "Zambon, Maria C." SCOPUS. Retrieved 14 June 2021. h-index:75
  3. ^ a b "Maria Zambon, Public Health England, UK". ISIRV. Retrieved 25 April 2020.
  4. ^ Sugrue, R. J.; Bahadur, G.; Zambon, M. C.; Hall-Smith, M.; Douglas, A. R.; Hay, A. J. (1990). "Specific structural alteration of the influenza haemagglutinin by amantadine". The EMBO Journal. 9 (11): 3469–3476. doi:10.1002/j.1460-2075.1990.tb07555.x. PMC 552095. PMID 2209554.
  5. ^ Sample, Ian (24 April 2020). "Who's who on secret scientific group advising UK government?". The Guardian. Retrieved 24 April 2020.
  6. ^ De Groot, Raoul J.; Baker, Susan C.; Baric, Ralph S.; Brown, Caroline S.; Drosten, Christian; Enjuanes, Luis; Fouchier, Ron A. M.; Galiano, Monica; Gorbalenya, Alexander E.; Memish, Ziad A.; Perlman, Stanley; Poon, Leo L. M.; Snijder, Eric J.; Stephens, Gwen M.; Woo, Patrick C. Y.; Zaki, Ali M.; Zambon, Maria; Ziebuhr, John (2013). "Commentary: Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group". Journal of Virology. 87 (14): 7790–7792. doi:10.1128/JVI.01244-13. PMC 3700179. PMID 23678167.
  7. ^ Corman, Victor M.; Landt, Olfert; Kaiser, Marco; Molenkamp, Richard; Meijer, Adam; Chu, Daniel KW; Bleicker, Tobias; Brünink, Sebastian; Schneider, Julia; Schmidt, Marie Luisa; Mulders, Daphne GJC; Haagmans, Bart L.; Van Der Veer, Bas; Van Den Brink, Sharon; Wijsman, Lisa; Goderski, Gabriel; Romette, Jean-Louis; Ellis, Joanna; Zambon, Maria; Peiris, Malik; Goossens, Herman; Reusken, Chantal; Koopmans, Marion PG; Drosten, Christian (2020). "Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR". Eurosurveillance. 25 (3). doi:10.2807/1560-7917.ES.2020.25.3.2000045. hdl:10067/1665670151162165141. PMC 6988269. PMID 31992387. Retrieved 14 June 2021. (This paper currently has an expression of concern, see doi:10.2807/1560-7917.ES.2020.25.48.2012031, PMID 33272356,  Retraction Watch. If this is an intentional citation to a such a paper, please replace {{expression of concern|...}} with {{expression of concern|...|intentional=yes}}.)
  8. ^ "Diagnostic detection of 2019-nCoV by real-time RT-PCR" (PDF). WHO. 17 January 2020. Retrieved 14 June 2021.
  9. ^ "Professor Maria Zambon FMedSci". Academy of Medical Sciences. Retrieved 25 April 2020.
  10. ^ "National Infection Service - latest information regarding 2019-nCoV coronavirus". Royal College of Pathologists. 7 February 2020. Retrieved 25 April 2020. Professor Maria Zambon BSc BMBCh PhD FRCPath FMedSci
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